Chorioamnionitis Intrapartum

Diagnosis Common Pathogens Drug(s) of First Choice Alternative Drug(s) Comments Expected Duration

Chorioamnionitis Intrapartum

Bacteroides
Prevotella bivia

Group B & A streptococci
Enterobacteriaceae
M. hominis

1st line:
Cefoxitin

2nd line:
Ampicillin

+
Gentamicin

For severe PCN allergy:
If GBS negative or Clindamycin sensitive GBS:
Clindamycin
PLUS
Gentamicin

If GBS positive and Clindamycin resistant OR resistance unknown:
Vancomycin
PLUS
Gentamicin