Patient Population: Adult
| Diagnosis | Common Pathogens | Drug(s) of First Choice | Alternative Drug(s) | Comments | Expected Duration |
|---|---|---|---|---|---|
|
Chorioamnionitis Post-partum (vaginal delivery) |
Bacteroides Prevotella bivia Group B & A streptococci Enterobacteriaceae M. hominis |
1st line: Cefoxitin 2nd line: Ertapenem |
For severe PCN allergy: If GBS neg or Clindamycin-sensitive GBS: PLUS IF GBS pos and Clinda resistant/resistance unknown: PLUS |
Antibiotics are continued for one dose after delivery unless the patient is diagnosed with endometritis | |
|
Chorioamnionitis Post-partum (Cesarean delivery) |
Bacteroides Prevotella bivia Group B & A streptococci Enterobacteriacae M. hominis |
1st line: Cefoxitin 2nd line: Ertapenem |
For severe PCN allergy: Regardless of GBS status: PLUS PLUS Metronidazole |
Continue antibiotics until afebrile for 24 hours |