Acute prostatitis

Diagnosis Common Pathogens Drug(s) of First Choice Alternative Drug(s) Comments Expected Duration

Acute prostatitis

Enterobacteriaceae (E. coli)

N. gonorrhoeae

C. trachomatis

Ciprofloxacin  OR

Levofloxacin

OR

Trimethoprim/sulfamethoxazole
 

Antibiotic penetration in the acute inflammatory state is adequate for most antibiotics.

Test for N. gonorrhoeae and C. trachomatis in sexually active patients

2-4 weeks

Cultures should be obtained and definitive therapy should be based on sensitivities