UCSF Medical Center Antimicrobial Susceptibility: Gram-positives Among Inpatients 2015

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N/A -testing NOT APPLICABLE to organism. GEN -gentamicin, T/S-trimethoprim/sulfamethoxazole, CIP-ciprofloxacin, PCN -penicillin, NAF-nafcillin, ERY-erythromycin, CLIN-clindamycin, DOX-doxycycline, VANC-vancomycin

Values are % of strains testing susceptible to listed antibiotic.  Staphylococcl results are for all inpatient locations and culture sites.  Streptococcus pneumoniae results are from inpatient and outpatient sites combined.

Organism

Total

Isolates

PCN

NAF

ERY

CLIN

CIP

DOX

T/S

VANC

Staphylococcus aureus

352

0

61

46

66

59

94

96

100

MRSA

136

N/A

N/A

10

44

19

90

95

100

MSSA

216

0

100

69

80

85

97

97

100

Staphylococcus epidermidis

120

0

31

2

63

38

87

48

100

Streptococcus pneumoniae

 54

See below

N/A

 83

 75

N/A

 61

 78

100

 

Streptococcus pneumoniae beta-lactam sensitivities:

-Across isolates from all sites, 83% (45/54 isolates) were PCN susceptible. 100% (54/54) were susceptible to levofloxacin. There was 1 isolate from the CSF, which was penicillin-resistant and ceftriaxone and vancomycin-susceptible.

NOTE: For the treatment of meningitis, pending susceptibilities, VANC empirically should be added to the regimen since failures (due to highly resistant isolates) have been reported with ALL third generation cephalosporins.