Hospitalized Adults: Skin and Soft Tissue Infections: Cellulitis

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Doses provided in this table are for patients with normal renal and hepatic function. Click on drug link to go to dosing guidelines.  Some antimicrobials are restricted (ID-R).  Click on link for guidelines on obtaining authorization.

Diagnosis

Common Pathogens

Drug(s) of First Choice

Alternative Drug(s)

Comments

Cellulitis

Group A streptococci

Other beta-hemolytic streptococci

S.aureus

Vancomycin

Alternatively:

Cefazolin 1 g IV q8h if patient is stable and cellulitis is not associated with an abscess or other purulent focus of infection 

 

Empirical Gram-negative and/or anaerobic coverage is not routinely indicated.