Hospitalized Adults: Intravascular Catheter-Related Infections

PrintPrintPDFPDF

Doses provided in this table are for patients with normal renal and hepatic function. Click on drug link to go to dosing guidelines.  Some antimicrobials are restricted (ID-R).  Click on link for guidelines on obtaining authorization.

Diagnosis

Common Pathogens

Drug(s) of First Choice

Alternative Drug(s)

Comments

Line-related bacteremia 

 

S. epidermidis

S. aureus

Enterococci spp.

Gram-negative rods*

Yeast**

Vancomycin

WITH OR WITHOUT* one of:

Piperacillin/tazobactam

ID-R: SFGH

4.5 g IV q6h

OR

CefepimeID-R: SFGH VASF 2 g IV q8h

For severe PCN allergy:

Vancomycin

WITH OR WITHOUT* one of:

Aztreonam ID-R: SFGH 2 g q8h

Remove the offending intravascular device immediately, if possible.

 

*Consider Gram-negative coverage for immunocompromised patients or those with prolonged hospitalization, recent antibiotic exposure or sepsis.

 

**Contact ID or ID Pharmacy if yeast is present.