Hospitalized Adults: Central Nervous System Infections: Epidural Abscess

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Doses provided in this table are for patients with normal renal and hepatic function. Click on drug link to go to dosing guidelines.  Some antimicrobials are restricted (ID-R).  Click on link for guidelines on obtaining authorization.

Diagnosis

Common Pathogens

Drug(s) of First Choice

Alternative Drug(s)

Comments

Epidural Abscess

S. aureus

Streptococci (anaerobic or aerobic)

E.coli

 

Ceftriaxone

2 g IV q12h

PLUS

Vancomycin

 

For severe PCN allergy:

AztreonamID-R: SFGH 2 g IV q8h

PLUS

Vancomycin

 

ID consultation recommended.