Adult Outpatients: Skin and Soft-Tissue Infections: Abscess

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Doses provided in this table are for patients with normal renal and hepatic function. Click on drug link to go to dosing guidelines.  Some antimicrobials are restricted (ID-R).  Click on link for guidelines on obtaining authorization.

Diagnosis

Common Pathogens

Drug(s) of First Choice

Comments

Abscess 

S. aureus

Uncomplicated:

Incision and drainage, no antibiotics needed

 

Complicated:

Incision and drainage

PLUS

TMP/SMX 1-2 DS tablets PO BID

OR

Doxycycline 100 mg PO BID

Give antibiotics for complicated abscess

  • Abscess is large (> 5 cm) or incompletely drained
  • There is significant surrounding cellulitis
  • Systemic signs and symptoms of infection are present
  • Patient is immunocompromised

 

7-10 days of therapy is generally adequate